Laurentiu Spiridon
Institute of Biochemistry of the Romanian Academy, Romania
Biography
Laurentiu Spiridon is currently working at the Institute of Biochemistry of the Romanian Academy, Romania. He has his work focused on creating a remote homology modelling method, SLIDE, a structural glycobiology software suite, Glyco Pack and a database of glycosylation sites named SAGS as. He is also working on optimizing the software package Robo Sampling which was developed during his Postdoctoral Fellowship (2013 - 2016) in Professor David Minh’s group at the Illinois Institute of Technology (IIT) in Chicago, USA. At IIT, he focused on developing enhanced sampling methods and for this software specifically - generalized coordinates Hamiltonian Monte Carlo using spatial operator algebra. His areas of interests include: force field development, more precisely he developed and implemented a flat-bottom harmonic potential that restricts ligands within the range of a specific pose during binding.
Abstract
Abstract : Generalized coordinates hybrid Monte Carlo using high speed robotics algorithms